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Updated on Sep 27, 2024 Share

Proteins are large molecules in the body that play a critical role in virtually everything that happens. Movement, maturation, and other processes are not possible without a lot of proteins. Protein therapy is a form of treatment that involves sending in well-structured proteins to a precise target location to repair or replace damaged ones. This is one of the most widely used treatment methods due to its accuracy and lack …

Updated on Dec 9, 2024 Share

Cell Loss in Separation and Isolation Assays When performing research, it’s easy to forget that individual cells are living things. Each one has its own role and internal organelles that help it survive from day-to-day. The process of isolating cells for research and removing them from their ideal environment can be harmful. Significance With each lost cell the sample becomes less valuable. Often, the goal of isolating cells is to …

Updated on Feb 5, 2025 Share

Adoptive Immunotherapy The human body is naturally equipped with tools to fight off infectious diseases and harmful pathogens. An intricate system of cells works together to facilitate an immune response that defends the body from dangerous substances. Although this process is both fast and adaptive, there are limitations to what it can do. Certain diseases, such as cancer, can intensify to a point where the immune system is no longer …

Updated on Mar 10, 2022 Share

Early Data from Akadeum’s RNA Extraction Project for Pooled Saliva Samples   Current COVID-19 saliva testing is limited. Akadeum’s microbubbles aim to change everything. At Akadeum Life Sciences, we are actively working to develop an innovative cell separation approach that makes pooled saliva testing possible – in an accurate and cost-effective way. We have expanded our microbubble platform by functionalizing our revolutionary buoyancy-activated separation (BACS™) technology for RNA isolation in …

Updated on Aug 21, 2023 Share

T Cell Receptors T Cell Receptors (TCRs) are protein complexes found on the surface of T cells or T lymphocytes responsible for recognizing antigens on foreign substances. Without TCRs, the immune system would not be able to successfully identify and fight infectious disease. Structure of TCRs T cell receptors are members of the immunoglobulin family; a large group of proteins responsible for binding to and recognizing antibodies. Within the chains …

Updated on Nov 28, 2023 Share

Optimizing a cell separation method is critical for many researchers. There are various ways to sort different types of cells, and the best methodology often depends on the cell subset. One of the quicker and more cost-effective ways to sort a sample based only on physical characteristics is using centrifugation.

Updated on Aug 21, 2023 Share

Circulating Tumor Cells When a tumor is present in the human body, cells naturally eliminate in the beginning stages of formation and growth. These residual fragments in the bloodstream are called circulating tumor cells (CTCs). CTCs are highly valued in the medical research community because they can alert doctors to the presence of a tumor before imaging. By working backwards, scientists can use CTCs to identify the approximate size and …

Updated on Feb 15, 2024 By Jason Ellis, PhD Share

In the fast-evolving world of biomedical research, the ability to accurately classify and analyze cells is pivotal. Cell isolation and sorting technologies provide essential tools for researchers in several prominent fields, including immunology, cancer research, and stem cell studies.  Among the most prominent techniques are fluorescence-activated cell sorting (FACS), magnetic-activated cell sorting (MACS), and the emerging buoyancy-activated cell sorting (BACS™). Each of these methods has unique advantages and challenges, shaping …

Updated on Nov 21, 2024 Share

Cytotoxic T Cells A cytotoxic T cell (CD8+ T cell) is a type of T cell responsible for eliminating substances the immune system identifies as harmful. Cytotoxic T cells play a critical role in limiting infections and bacteria in the body. Functions of Cytotoxic T Cells Viruses and other bacteria attack by multiplying and spreading diseases as infected cells. Once a cell is infected, there is no way for antibodies …

Updated on Nov 21, 2024 Share

Have you run into this problem before? You’re studying a rare or limited cell population. You prepare your sample and run fluorescence activated cell sorting (FACS™). It’s time consuming. The longer it takes, the more cell death happens. You’re having trouble collecting enough cells for downstream applications. You’re frustrated. You wish there were a better way. A magic wand, perhaps. You’re not alone. Sample preparation is critical to the success …