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Cell Culture Contamination: Identifying Mycoplasma, Fungus, and Bacteria in a Growth Medium

Updated on Aug 21, 2023

Colleagues working in a science lab

Contamination in Cell Cultures Medical research is an ever-evolving field that continues to contribute to the advancement of human health. A key component of this type of research is the process of cell culturing, which involves the isolation and expansion of a cell population. The cell culture process begins with the extraction of a target sample. Once the desired cells have been acquired, they must be purified to minimize contamination. …

Primary T Cell Culture and Expansion

Updated on Nov 29, 2023 By Dominique Badea, PhD

Microscopic View of T Cells

T Cells are a critical component of the immune system. They play a pivotal role in the body’s defense against infections, cancer, and a variety of other diseases. To harness the full potential of these immune warriors, scientists have worked hard on perfecting the art of T cell culturing. Research and development of new immunotherapies requires robust techniques to purify and culture T cells. This article serves as a primer …

T Cell Immune Response and Cytokine Storm in COVID-19 Patients

Updated on Aug 21, 2023

COVID-19

T Cells and COVID-19 The body is naturally equipped with a variety of T lymphocytes that work together to fend off harmful pathogens. The human immune system routinely battles mild diseases with recognizable antigens. By attacking the source of a virus or bacteria, damage to healthy cells can be minimized. The T cell immune response to COVID-19 is different because it’s caused by an RNA virus (SARS-CoV-2). RNA viruses insert …

Using Akadeum’s Mouse T Cell Isolation Kit to study immunological processes of vaccine mediated immunity

Updated on Aug 18, 2022

Use of Akadeum’s gentle Mouse T Cell Isolation kit results in a high purity T cell population while retaining cellular viability. Get an inside look at how Akadeum’s products perform in real-world research that is happening in laboratories across the country. A research group, led by Evan Scott at Northwestern University, used the Mouse T Cell Isolation Kit from Akadeum Life Sciences to obtain a high purity isolation of viable, …

Using Akadeum’s Mouse B Cell Isolation Kit to study B cell differentiation into plasma cells

Updated on Aug 18, 2022

Akadeum’s gentle Mouse B Cell Isolation kit produces high purity B cell population without affecting physiology or differentiation potential. Get an inside look at how Akadeum’s products perform cell separation in real-world research that is happening in laboratories across the country. A research group at the University of Pennsylvania used the Mouse B Cell Isolation Kit from Akadeum Life Sciences in their research into the mechanisms that underlie the differentiation …

The Role of B Cells and T Cells in COVID-19 Immune Response & T Cell Immunity in COVID-19 Patients

Updated on Aug 17, 2023

Recent developments in COVID-19 immunology research look at the role T cells and B cells play in immune response to infection with SARS-CoV-2. The global scientific community has made great strides in characterizing the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for coronavirus disease 2019 (COVID-19). There are several studies that have been published in recent months that take a closer look at how …

Akadeum Microbubbles: The Novel Approach to COVID Research (Webinar Dec 16)

Updated on Sep 13, 2023

The emergence of COVID-19 has changed life as we know it the world over. This is a fast-moving and deadly pandemic that requires novel, next-generation technology to enable ongoing research and advanced diagnostic testing. Join us on December 16 to get an inside look at how Akadeum’s products and cell separation technology are contributing to the solutions of tomorrow. In this webinar, we will cover:  An overview of the microbubble …

Using Akadeum’s Mouse B Cell Isolation Kit to study autoreactive B cell activation and differentiation

Updated on Aug 18, 2022

“The resulting sample looked perfect after using microbubbles – very happy with the product.” Get an inside look into how products from Akadeum Life Sciences perform in real-world research that is happening in laboratories across the country. A research group at the University of California San Francisco recently used the Mouse B Cell Isolation Kit from Akadeum Life Sciences in the course of their research into understanding how autoreactive B …

Improving Cell Separation for Single Cell RNA Sequencing

Updated on Aug 21, 2023

Scientist in a lab

RNA-Sequencing Medical advancements have provided researchers with strategies that change the way in which we understand biology. Scientists are now capable of studying coded protein patterns at a genomic level. RNA-sequencing (RNA-seq) is the process of detecting and analyzing the messenger RNA (mRNA) of a cell type. The range of mRNA molecules present in an organism is also known as the transcriptome. Identifying a biological transcriptome can give a better …

TIL Therapy: Revolutionizing Solid Tumor Treatment

Updated on Mar 13, 2024

Tumor-infiltrating lymphocyte (TIL) therapy is a modern cancer treatment used to combat notoriously hard-to-treat solid tumors. Like other adoptive cell therapies, TIL harnesses the body’s immune system to combat malignancies by using T cells, a type of white blood cell integral to immune response. Except in TIL therapy, these T cells are directly extracted from tumors. Having survived the tumor microenvironment, these lymphocytes are already primed to recognize and attack …

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