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March 2020 Share

Cell isolation methods and technologies use either a positive or negative cell separation approach. Here are some of the differences when considering a cell separation approach:

March 2020 Share

Blood separation is a key part of many life sciences. Researchers in clinical labs and other biotechnical roles commonly analyze blood cells, but to perform this research, whole blood must first be separated into its components. By isolating and enriching target cells from plasma, scientists can then detect diseases, study immunological functions, and further process specific cell types. Components of Whole Blood Whole blood consists of red cells, white cells, …

March 2020 Share

Cell isolation—also referred to as cell separation or cell sorting—is the process of isolating one cell population from other cells in a heterogeneous biological sample. Targeted cells are identified, isolated, and then separated according to their type.

November 2016 Share

If you are reading this, you probably already understand or at least have a very good idea of what cell sorting and cell separation is. Still, you would be surprised by how many times we get asked questions like, “What is the difference between cell sorting and cell separation?” We also get questions like, “What are the different ways to separate cells?” or “What is the difference between positive and …

February 2016 Share

Can microbubbles be pelleted by centrifugation? In short, no. At least, not a pellet that you would see at the bottom of your tube when you spin down cells. Here’s how it works.

February 2016 Share

We hear this question all the time: How many cells can a microbubble lift? For many users, the most important questions around microbubble-based separation have to do with how many microbubbles to add to a sample. Answering this question requires getting into the total lifting capacity of a microbubble. Part of the answer derives from how a microbubble engages cells, clumps of cells, or even larger structures such as spheroids …

January 2016 Share

Flotation is the driving principle behind our cell sorting technology. It’s hard to imagine many other physical phenomena that humans have more of an intuition for than floating and sinking. The exact same rules of floating and sinking apply to a stem cell being lifted from a sample on the back of Akadeum’s microbubbles. In principal, it is as simple as pair of water wings that keeps a two-year-old child …