Blog Category: Technical

What are microbubbles made of?

October 2016

blowing-bubbles

When we are out talking about Akadeum’s cell separation microbubbles, we come across a lot of people that think the microbubbles are purely made of a gas. While this is the common type of bubble that many of us are most familiar with, it is not the type of bubble used in separating cells. Glass Shells with a Gaseous Core Akadeum’s microbubbles are made of thin shells of glass with a …

Microbubbles and Centrifugation: How It Works

February 2016

beach-ball

Can microbubbles be pelleted by centrifugation? In short, no. At least not a pellet that you would see at the bottom of your tube when you spin down cells. Instead, what happens is anything with a density greater than water sinks and sinks faster when in a centrifuge. And anything with a density less than water rises and rises faster when in a centrifuge. How Microbubbles Float When Centrifuged So, …

The Physics of How Microbubbles Sort Cells

January 2016

child-in-swimming-pool

Flotation is the driving principle behind our cell sorting technology. It’s hard to imagine many other physical phenomena that humans have more of an intuition for than floating and sinking. The exact same rules of floating and sinking apply to a stem cell being lifted from a sample on the back of an Akadeum microbubble. In principal, it is as simple as pair of water wings that keeps a two-year-old …