Category: BACSTM Microbubble Technology and Workflow
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Published on Oct 28, 2025 Share Category: Introduction Videos, BACSTM Microbubble Technology and Workflow
Discover how Akadeum’s microbubble technology works in just four simple steps that deliver healthier, more potent cells for cell therapy manufacturing. Capable of processing over 50 billion cells in under an hour, Akadeum microbubbles enable gentle, scalable isolation and depletion directly in-bag or within closed systems. Designed for flexibility, microbubbles integrate seamlessly with industry-leading platforms like Cocoon®, Rotea™, Sepax™, and ExPERT GTx™, supporting workflows from research to manufacturing scale. See …
Published on Oct 28, 2025 Share Category: BACSTM Microbubble Technology and Workflow
Akadeum CEO Brandon McNaughton returns to Cell & Gene’s Meeting on the Mesa to present significant regulatory accomplishments, clinical milestones, and recent data from industry collaborators demonstrating how better cell separation is the key to better therapies. Presentation Highlights: Akadeum’s microbubble-based cell separation technology is the first and only separation technology that works entirely “in bag” for untouched, negative selection without the need for magnetics and is compatible with industry-leading …
Published on Oct 21, 2025 Share Category: BACSTM Microbubble Technology and Workflow
Akadeum’s buoyancy-based cell separation allows for an unique in-bag negative selection protocol that can be easily integrated into workflows that already incorporate cell processing equipment, such as the Cytiva Sepax. A Sepax-integrated workflow with Akadeum technology allows for a closed system process that can be scaled to meet any and all manufacturing needs. Utilizing standard Sepax protocols, Akadeum’s Human T Cell Leukopak Isolation Kit – GMP protocol can be initiated …
Updated on Oct 31, 2025 Share Category: What’s New, BACSTM Microbubble Technology and Workflow
Cells are isolated in-bag then transferred from the bag to any Wilson Wolf G-Rex® bioreactor. Cells are then electroporated using the MaxCyte ExPERT GTx® Instrument. Electroporation can be done at both small and large scale, with the capability of sterile tube welding to facilitate larger scale workflows. Combining technologies, the result is highly viable cells with greater killing potential.
Updated on Nov 4, 2025 Share Category: BACSTM Microbubble Technology and Workflow
In this video, Akadeum Life Sciences Sr. Field Application Scientist Crisha Christensen demonstrates how to combine Akadeum’s Human T Cell Leukopak Isolation Kit – GMP with the Wilson Wolf G-Rex® bioreactor to create a seamless, closed-system workflow—from isolation to expansion. The video highlights how easy it is to transition isolated T cells directly from the processing bag into a G-Rex bioreactor, maintaining cell quality, sterility, and GMP compliance every step …
Updated on Nov 6, 2025 Share Category: BACSTM Microbubble Technology and Workflow
In this video, Akadeum Life Sciences’ Senior Field Application Scientist Crisha Christensen demonstrates how to perform closed-system, in-bag T cell isolation using Akadeum’s Human T Cell Leukopak Isolation Kit – GMP, followed by cell harvest with the Thermo Fisher CTS Rotea® Counterflow Centrifugation System. This combined workflow simplifies manual processing, shortens handling time, and supports GMP-compliant manufacturing without introducing additional instruments or open steps. From In-Bag Isolation to Rotea Harvest …
Updated on Nov 4, 2025 Share Category: BACSTM Microbubble Technology and Workflow
In this step-by-step video, Akadeum Life Sciences Sr. Field Application Scientist Crisha Christensen demonstrates how to perform a GMP-compliant, manual, closed-system T cell isolation using the Human T Cell Leukopak Isolation Kit – GMP. Designed for use in early clinical research and scalable through commercial manufacturing environments, this workflow offers unmatched flexibility with cost and time savings — no magnets, columns, or capital equipment required. A Closer Look at the …
Updated on Sep 19, 2025 Share Category: What’s New, BACSTM Microbubble Technology and Workflow, Featured Products
Take a deeper dive into the Alerion™ and the BioRise™ consumable with our Senior Director of R&D, Dr. Bill Lloyd. Bill shows you how to scale up your cell isolations simply, quickly, and gently.
Updated on Sep 19, 2025 Share Category: BACSTM Microbubble Technology and Workflow
Explore the components of the Alerion™ Microbubble Cell Separation System in this minute and a half video, and learn how the components help scale up your cell therapy workflows.
Updated on Sep 19, 2025 Share Category: BACSTM Microbubble Technology and Workflow
Akadeum’s microbubbles represent a breakthrough in process improvement for CAR-T / TCR & other cell therapy processes.