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Nucleic Acid Extraction

Akadeum’s microbubble platform utility now includes nucleic acid capture protocols. This can be functionalized for nonspecific capture as well as specific sequence capture and can enable streamlined positive selection or depletion protocols.



Application areas for this technology can include:

  • Respiratory Dx: For example, using RNA extraction for viral/bacterial testing
  • Extraction: For example, wastewater surveillance and microbiome research
  • Liquid Biopsy: For example, capturing circulating DNA for oncology
  • Single Cell Analysis: For example, depletion of cell-free RNA or other molecular contamination

RNA detection is a powerful tool to identify the presence of viruses, including influenza, SARS-CoV-2, and other common pathogens.

One application for Akadeum’s Nucleic Acid Extraction capabilities is in pooled saliva for viral detection – where pooling of saliva samples from groups of 10-20 unique individuals can enable fast and easy, resource-efficient surveillance of facilities to provide near real-time alerts to active infections.

Akadeum’s microbubble technology enables the interrogation of the full fluidic volume for more complete and representative RNA capture using a streamlined process that is easily integrated into existing workflows.


Learn more about Akadeum’s Nucleic Acid Extraction from Pooled Saliva:

Complete the form below to access download links to additional data and resources, including

Akadeum’s Whitepaper:
Microbubble Optimization for SARS-CoV-2 RNA Extraction in Saliva Samples Enables Advanced Diagnostic Opportunities

Poster presented at the National Cancer Institute Meeting in 2021:
Nucleic Acid Extraction with Microbubbles from Saliva Enables Enrichment from Larger Sample Volume

Recorded Webinar:
Reaching New Heights with Nucleic Acid Extraction

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