Case Studies

Published on Jun 17, 2025 Share

Akadeum’s microbubble kits are built with universal compatibility and repeatable top performance in mind. Whether you’re seeking to isolate cells at the point of collection, running a manual process or using advanced automation, our technology works within your current infrastructure and expands your capability anywhere—an advantage achieved only with microbubbles. Learn more and see the data, in this booklet providing an overview of Akadeum’s microbubble technology for cell therapy workflows.

Updated on Jun 17, 2025 Share

Poseida Therapeutics, a clinical-stage allogeneic-focused therapeutic developer leveraging proprietary technologies to create life-saving cell therapies, selected the Akadeum platform, consisting of the new Alerion™ Microbubble Cell Separation System, the innovative BioRise™ consumable, and the Human T Cell Leukopak Isolation Kit, to improve workflows for its cancer and genetic disease solutions. A critical step in developing these therapies is isolating T cells from leukapheresis material. This requires an isolation process that …

Updated on Jun 17, 2025 Share

Comprehensive Cell Solutions (CCS), a business unit of the New York Blood Center Enterprises, is a Contract Development and Manufacturing Organization. CCS recently evaluated the Alerion™ Microbubble Cell Separation System, the BioRise™ consumable, and the negative selection Human T Cell Leukopak Isolation Kit. CCS is dedicated to streamlining their manufacturing process and requires a platform that is flexible, efficient, and consistently delivers high-performance results to meet the demands of cell …

Updated on Jun 17, 2025 Share

Akadeum Life Sciences has partnered with a cell therapy AlerionTM Microbubble Cell Separation System beta customer to help their team develop an improved method for T cell banking. The company faces significant challenges in recovery, purity, and processing time with its existing manual methods, and Akadeum’s AlerionTM is well suited to overcome the challenges with its proven superior cell recovery, purity, and scalability. The Challenge To develop and deliver effective …

Published on Jun 17, 2025 Share

The Alerion™, in combination with the BioRise™ consumable and microbubble technology, provides the first solution for negative selection at scale. With kits for cell separation, activation, and depletion, Akadeum’s technology is elevating the field of cell therapy and recovering better cells for downstream processing. With data from Akadeum and key strategic partners, this booklet walks potential Alerion™ users through findings speaking to recovery, purity, time, and much more.

Updated on Jun 17, 2025 Share

A cell therapy company sought to improve its CD3+ T cell isolation process. To address the challenges it faces with its current method for recovery, purity, and processing time, it partnered with Akadeum Life Sciences to evaluate the Alerion™ Microbubble Cell Separation System in conjunction with the BioRise™ consumable and Human T Cell Leukopak Isolation Kit. They chose to evaluate the Alerion™ Microbubble Cell Separation System due to: Better cell …

Updated on Jun 17, 2025 Share

Use of Akadeum’s gentle and effective Human CD4+ T Cell Isolation Kit results in a highly enriched sample of human CD4+ T cells, enabling detection and isolation of low-abundance, antigen-specific CD4+ T cells in patient samples. A research group led by Professor Georg Lauer at Massachusetts General Hospital and the Harvard Medical School recently used Akadeum’s Human CD4+ T Cell Isolation Kit to obtain high purity enrichment of viable, healthy …

Updated on Jun 17, 2025 Share

Use of Akadeum’s gentle Mouse B Cell Isolation kit results in a highly enriched sample of B cells that are healthy and retain their antigen-presenting capabilities. A researcher, Ichwaku Rastogi, from the Doug McNeel Lab at the University of Wisconsin, used the Mouse B Cell Isolation Kit from Akadeum Life Sciences to obtain a high purity isolation of viable, healthy B cells. The researchers are looking into targeted delivery of …

Updated on Jun 17, 2025 Share

“The resulting sample looked perfect after using microbubbles – very happy with the product.” Get an inside look into how products from Akadeum Life Sciences perform in real-world research that is happening in laboratories across the country. A research group at the University of California San Francisco recently used the Mouse B Cell Isolation Kit from Akadeum Life Sciences in the course of their research into understanding how autoreactive B …

Updated on Jun 17, 2025 Share

Akadeum’s gentle Mouse B Cell Isolation kit produces high purity B cell population without affecting physiology or differentiation potential. Get an inside look at how Akadeum’s products perform cell separation in real-world research that is happening in laboratories across the country. A research group at the University of Pennsylvania used the Mouse B Cell Isolation Kit from Akadeum Life Sciences in their research into the mechanisms that underlie the differentiation …