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Updated on Jun 10, 2025 | Published on Feb 10, 2025 Share

B cell acute lymphoblastic leukemia (B-ALL) is an aggressive cancer affecting the bone marrow and blood. When traditional treatments like chemotherapy and radiation fall short in relapsed or refractory cases, CAR T cell therapy provides a transformative new option, offering hope via T cells engineered to target and destroy cancerous B cells. At Akadeum Life Sciences, our innovative cell isolation technologies, including the AlerionTM Microbubble Cell Separation System and our …

Updated on Jun 9, 2025 | Published on Jan 24, 2025 Share

Whether for basic science or advanced applications like CAR T therapy, the efficiency and precision of cell isolation techniques can make or break research outcomes and therapeutic timelines. While magnetic beads have long served as the backbone of T cell isolation, their scalability, speed, and cell health preservation limitations are becoming increasingly apparent. Akadeum Life Sciences’ Alerion™ Microbubble Cell Separation System addresses these challenges with innovative, scalable solutions that integrate …

Updated on Jun 9, 2025 | Published on Jan 10, 2025 Share

Rising cancer rates have been featured heavily in the news this year, especially among younger adults. As cancer rates continue to climb, the need for innovative treatments has never been more pressing. Over recent years, immunotherapy, particularly CAR T cell therapy, emerged as a promising approach, offering renewed hope to patients facing challenging diagnoses through a personalized approach.  However, the increasing demand for these therapies revealed significant bottlenecks in the …

Updated on Jun 10, 2025 | Published on Dec 13, 2024 Share

Unlocking the Power of Precision Gene Editing for CAR T Cell Therapy Precision is paramount in CAR T cell therapy. As a lab-based cancer treatment technique, CAR T therapy hinges on scientists’ ability to genetically engineer T cells to express receptors that target cancer cells.  T cell populations must be viable and robust enough to undergo gene editing effectively. Therefore, high-quality cell isolation is essential to ensuring CAR T cell …

Event Start Date: JAN 13, 2025 Share

Innovation takes center stage on January 13th, 2025, as Dr. Brandon McNaughton, CEO of Akadeum Life Sciences, presents the performance of the Alerion™ Microbubble Cell Separation System at Biotech Showcase 2025 in San Francisco. Designed to address unmet cell therapy market needs of scale, gentleness, speed and performance in cell separation, the Alerion system is redefining what’s possible in research and therapeutic applications. Akadeum’s technology and products have been and …

Updated on Jun 9, 2025 | Published on Dec 9, 2024 Share

The Role of T Cell Depletion in Optimizing T Cell Recovery As CAR T cell therapies continue to transform cancer treatment, one critical challenge is maximizing the purity and functionality of CAR T cell cultures. T cells are engineered to target and destroy cancer cells in these therapies, making them a powerful option for cancers like leukemia and lymphoma.  However, an essential step in processing CAR T cells in allogeneic …

Event Start Date: JAN 20, 2025 Share

Akadeum Announces Alerion™ Microbubble Cell Separation System Availability  After a year of testing onsite with therapeutic developers, Akadeum Life Sciences, a leader in cell separation, is excited to announce the opportunity for the scientific community to purchase the Alerion™ Microbubble Cell Separation System for use in research through clinical settings. Confirmed by customers to be the highest capacity, fastest, most gentle cell isolation system ever built, the successful Alerion™ early …

Updated on Aug 20, 2025 | Published on Nov 14, 2024 By Jason Ellis, PhD Share

Clonal expansion is the process of rapid cell division resulting in the multiplication of genetically identical cell clones from a single parent cell. In immunology, clonal expansion is a critical process that allows the immune system to produce large numbers of T cells to fight infections. This exponential growth provides a robust concentration of specific genetic material that aids immune and developmental processes. Clonal expansion replaces damaged or worn tissues …

Updated on Aug 20, 2025 | Published on Nov 8, 2024 Share

T cells, or T lymphocytes, are a critical component of the immune system, with several different types playing unique roles in defending the body. The main types of T cells include helper T cells, cytotoxic T cells, regulatory T cells, and memory T cells, each specialized to recognize and respond to various pathogens. These cells mature in the thymus and are released into the bloodstream as naïve T cells, prepared …

Updated on May 18, 2025 | Published on Nov 6, 2024 Share

When researchers unlock the secrets of T cells, their discoveries often pave the way for groundbreaking advancements in immunotherapy. Antigen-specific T cells, in particular, recognize and neutralize specific threats like pathogens and cancer cells. Their role in targeted immune responses makes them essential in modern immunotherapy and vaccine development. If antigen-specific T cells are crucial for therapies, effectively isolating them may be the key to their success. Emerging Research Applications …