Microbubbles for Mouse RBC Depletion (Early Access)

Are you struggling with RBC contamination? Are lysis buffers damaging target cells or disturbing their normal physiology?

Stop losing your precious cells to outdated magnetic processing.

Akadeum’s revolutionary microbubble approach removes 99% of mouse red blood cell (RBC) contamination in a fast and easy workflow that maintains the health and physiology of delicate cells of interest with exceptional yield. Simply mix to bind, spin to separate, and aspirate to discard.

Akadeum’s Mouse RBC Depletion Microbubbles are designed to clean up samples such as spleen or other lymphoid tissue preparations with RBC contamination. These microbubbles target Ter119 markers for highly-specific binding with erythrocytes. Upon engaging the undesired RBCs, Akadeum’s microbubbles gently float these cells to the top of the sample for easy removal, leaving the untouched cells of interest happy, healthy, and ready for downstream use.

 

 

Our microbubbles are mixed into your sample where they grab onto the contaminating RBCs. Using the power of gravity (they float!), the microbubbles lift the RBCs to the top of the sample container for removal. It’s really that simple! Your target cells remain untouched and ready for downstream use.

Fast Processing · Happy, Healthy Cells · Improved Results

 


 

Experience the Benefits of a Microbubble Workflow

Akadeum’s microbubble approach aims to maximize yield, reduce processing time, and maintain the health and physiology of delicate cells of interest. And we do all of this while eliminating the need for extra equipment like magnets and columns using a fast, easy workflow that takes place directly in the sample container – no extraneous pour-offs, no exposing delicate cells to external forces or rare earth magnets, no harsh chemicals. Our buoyant approach to separation eliminates many of the existing technical hurdles that are limiting improvements or effectiveness of processes today.

Why Microbubbles for RBC Depletion?

  • Akadeum’s Mouse RBC Depletion Kit removes up to 99% of red blood cell contamination while keeping target cells happy and viable.
  • The entire process can be done directly in the sample vial, no specialized equipment necessary. No magnets, no columns, no harsh chemicals or external forces.
  • The microbubbles are simply mixed into the sample where they bind to the contaminating RBCs. Using the power of gravity (the bubbles float!), the microbubbles lift the RBCs to the top of the sample container for removal.
  • The target cells of interest remain untouched (free from harsh forces and lysis buffers) and ready for downstream use.

Why Early Access?

Akadeum’s Mouse RBC Depletion Microbubble Kit is being launched as an Early Access program prior to full commercialization. This kit has been thoroughly validated and performs exceptionally well, and we are looking forward to working closely with the Early Access researchers using this product to gain insight and feedback on product characteristics like the number of cells processed and ideal kit configuration.

Questions we are looking to answer include:

  • Insight into research application and sample type
  • Typical sample numbers being processed
  • Downstream analysis / how the sample will be used following RBC depletion
  • Summary of experience with existing workflow vs. Akadeum RBC depletion workflow

Ready to Get Started?

Akadeum’s Mouse RBC Depletion Microbubbles are currently in Early Access – if you are interested in being an early access user, please submit the form below and we’ll be in touch! If you have any questions, you can book a meeting or reach out to info@akadeum.com.



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