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Category: Technical

FACS, MACS, and BACS™: What’s the Difference?

Updated on Sep 5, 2025 | Published on Oct 19, 2020 By Jason Ellis, PhD

scientists separating cells in a research lab

In the fast-evolving world of biomedical research, the ability to accurately classify and analyze cells is pivotal. Cell isolation and sorting technologies provide essential tools for researchers in several prominent fields, including immunology, cancer research, and stem cell studies.  Among the most prominent techniques are fluorescence-activated cell sorting (FACS), magnetic-activated cell sorting (MACS), and the emerging buoyancy-activated cell sorting (BACS™). Each of these methods has unique advantages and challenges, shaping …

Cytotoxic T Cells Role in the Immune System

Updated on Aug 20, 2025 | Published on Oct 19, 2020

T cells

Cytotoxic T Cells A cytotoxic T cell (CD8+ T cell) is a type of T cell responsible for eliminating substances the immune system identifies as harmful. Cytotoxic T cells play a critical role in limiting infections and bacteria in the body. Functions of Cytotoxic T Cells Viruses and other bacteria attack by multiplying and spreading diseases as infected cells. Once a cell is infected, there is no way for antibodies …

Performing Blood Cell Isolation from Whole Blood Samples

Updated on Aug 20, 2025 | Published on Mar 16, 2020

blood-samples

How Is Plasma Separated From Blood? Each blood cell type has its own unique purpose and function and separating the various blood components allows scientists to analyze specific cell types. For example, human leukocytes can be used to study immunological functions such as cytokine production and surface marker expression. Other blood components can be used to detect diseases. Once separated, blood cells can be further isolated into cell subsets. Components …

Microbubbles and Centrifugation: How It Works

Updated on May 19, 2025 | Published on Feb 2, 2016

beach-ball

Can microbubbles be pelleted by centrifugation? In short, no. At least, not a pellet that you would see at the bottom of your tube when you spin down cells. Here’s how it works.

How Many Cells Can a Microbubble Lift?

Updated on May 17, 2025 | Published on Feb 2, 2016

microscope

We hear this question all the time: How many cells can a microbubble lift? For many users, the most important questions around microbubble-based cell separation kits have to do with how many microbubbles to add to a sample. Answering this question requires getting into the total lifting capacity of a microbubble. Part of the answer derives from how a microbubble engages cells, clumps of cells, or even larger structures such …

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